Pelitinib (EKB-569)
Pelitinib (EKB-569) is a potent irreversible EGFR inhibitor with IC50 of 38.5 nM. Pelitinib (EKB-569) also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282 nM, 800 nM and 1255 nM, respectively. Phase2.
Trivial name | N/A |
Catalog Number | S1392 |
Molecular Formula | C18H15NO4 |
CAS# | 257933-82-7 |
Inchi | InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H,11H2,1H3,(H,20,21) |
Inchi Key | XTKDQPFUOFAMRL-UHFFFAOYSA-N |
SMILES | CN(CC1=CC=CC=C1)C2=CC3=C(C=C2)C=C(C(=O)O3)C(=O)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/Pelitinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/Pelitinib-EKB-569-chemical-structure-S1392.gif |