MGCD-265 analog
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S1361 |
| Molecular Formula | C26H20FN5O2S2 |
| CAS# | 875337-44-3 |
| Inchi | InChI=1S/C26H20FN5O2S2/c1-32-14-20(29-15-32)23-13-19-25(36-23)22(9-10-28-19)34-21-8-7-17(12-18(21)27)30-26(35)31-24(33)11-16-5-3-2-4-6-16/h2-10,12-15H,11H2,1H3,(H2,30,31,33,35) |
| Inchi Key | UFICVEHDQUKCEA-UHFFFAOYSA-N |
| SMILES | CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/mgcd-265-analog.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MGCD-265-chemical-structure-s1361.gif |