Zoledronic acid (Zoledronate)
Zoledronic acid (Zoledronate), a potent osteoclast inhibitor, induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Zoledronic acid (ZA) also induces autophagy.
| Trivial name | ZA, CGP-4244, GP42446A, ZOL 446 |
| Catalog Number | S1314 |
| Molecular Formula | C26H30F3N7O2 |
| CAS# | 118072-93-8 |
| Inchi | InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37) |
| Inchi Key | ODPGGGTTYSGTGO-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Zoledronic-Acid.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Zoledronic-Acid-Zoledronate-chemical-structure-S1314.gif |