Camptothecin (CPT)
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
| Trivial name | Campathecin, (S)-(+)-Camptothecin,NSC-100880 |
| Catalog Number | S1288 |
| Molecular Formula | C20H16N2O4 |
| CAS# | 7689-03-4 |
| Inchi | InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1 |
| Inchi Key | VSJKWCGYPAHWDS-FQEVSTJZSA-N |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Camptothecine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Camptothecine-chemical-structure-S1288.gif |