Camptothecin (CPT)
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
Trivial name | Campathecin, (S)-(+)-Camptothecin,NSC-100880 |
Catalog Number | S1288 |
Molecular Formula | C19H16BrNO2 |
CAS# | 7689-03-4 |
Inchi | InChI=1S/C19H16BrNO2/c20-15-9-18-17(22-10-23-18)8-14(15)19-13-6-3-5-11(13)12-4-1-2-7-16(12)21-19/h1-5,7-9,11,13,19,21H,6,10H2/t11-,13-,19+/m0/s1 |
Inchi Key | YOLTZIVRJAPVPH-MJLGCCKJSA-N |
SMILES | C1C=CC2C1C(NC3=CC=CC=C23)C4=CC5=C(C=C4Br)OCO5 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/Camptothecine.html |
Additional Information | https://file.selleck.cn/downloads/struct/Camptothecine-chemical-structure-S1288.gif |