Posaconazole
Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM. Posaconazole has a median terminal elimination half-life of 15-35 hours.
| Trivial name | SCH 56592, POS |
| Catalog Number | S1257 |
| Molecular Formula | C23H15F2NO2 |
| CAS# | 171228-49-2 |
| Inchi | InChI=1S/C23H15F2NO2/c1-13-21(23(27)28)18-12-16(24)10-11-20(18)26-22(13)15-8-6-14(7-9-15)17-4-2-3-5-19(17)25/h2-12H,1H3,(H,27,28) |
| Inchi Key | PHEZJEYUWHETKO-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=CC(=C2)F)N=C1C3=CC=C(C=C3)C4=CC=CC=C4F)C(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Posaconazole.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Posaconazole-chemical-structure-S1257.gif |