2-Methoxyestradiol (2-MeOE2)
2-Methoxyestradiol (2-MeOE2, NSC 659853, 2-ME2) depolymerizes microtubules and blocks HIF-1α nuclear accumulation and HIF-transcriptional activity. 2-Methoxyestradiol induces both autophagy and apoptosis in various carcinogenic cell lines.
| Trivial name | NSC 659853, 2-ME2 |
| Catalog Number | S1233 |
| Molecular Formula | C20H21N5O4 |
| CAS# | 362-07-2 |
| Inchi | InChI=1S/C20H21N5O4/c26-19(15-4-3-5-16(14-15)25(27)28)22-20-21-17-6-1-2-7-18(17)24(20)9-8-23-10-12-29-13-11-23/h1-7,14H,8-13H2,(H,21,22,26) |
| Inchi Key | QTCFYQHZJIIHBS-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCN2C3=CC=CC=C3N=C2NC(=O)C4=CC(=CC=C4)[N+](=O)[O-] |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/2-Methoxyestradiol(2ME2).html |
| Additional Information | https://file.selleck.cn/downloads/struct/2-Methoxyestradiol-chemical-structure-S1233.gif |