Topotecan HCl
Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.
| Trivial name | Nogitecan HCl, SKFS 104864A, NSC 609699 |
| Catalog Number | S1231 |
| Molecular Formula | C23H23N3O5.HCl |
| CAS# | 119413-54-6 |
| Inchi | InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1 |
| Inchi Key | DGHHQBMTXTWTJV-BQAIUKQQSA-N |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Topotecan-Hydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Topotecan-Hydrochloride-chemical-structure-S1231.gif |