Idarubicin HCl
Idarubicin HCl (4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL in a cell-free assay. Idarubicin induces mTOR-dependent cytotoxic autophagy.
| Trivial name | 4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl |
| Catalog Number | S1228 |
| Molecular Formula | C26H33NaO8 |
| CAS# | 57852-57-0 |
| Inchi | InChI=1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p -1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1 |
| Inchi Key | FQISKWAFAHGMGT-SGJOWKDISA-M |
| SMILES | CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+] |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Idarubicin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Idarubicin-HCl-chemical-structure-S1228.gif |