Etoposide
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.
| Trivial name | VP-16213,VP-16 |
| Catalog Number | S1225 |
| Molecular Formula | C27H38O3 |
| CAS# | 33419-42-0 |
| Inchi | InChI=1S/C27H38O3/c1-4-6-7-8-9-25(29)30-27(5-2)17-15-24-23-12-10-19-18-20(28)11-13-21(19)22(23)14-16-26(24,27)3/h2,18,21-24H,4,6-17H2,1,3H3/t21-,22+,23+,24-,26-,27-/m0/s1 |
| Inchi Key | APTGJECXMIKIET-WOSSHHRXSA-N |
| SMILES | CCCCCCC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34)C)C#C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Etopophos.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Etoposide-Etopophos-chemical-structure-S1225.gif |