Etoposide
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.
| Trivial name | VP-16213,VP-16 |
| Catalog Number | S1225 |
| Molecular Formula | C29H32O13 |
| CAS# | 33419-42-0 |
| Inchi | InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3 /t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1 |
| Inchi Key | VJJPUSNTGOMMGY-MRVIYFEKSA-N |
| SMILES | CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O |
| Size | 500mg |
| Supplier Page | http://www.selleckchem.com/products/Etopophos.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Etoposide-Etopophos-chemical-structure-S1225.gif |