YM201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue). YM-201636 suppresses the growth of liver cancer via the induction of autophagy.
| Trivial name | N/A |
| Catalog Number | S1219 |
| Molecular Formula | C25H21N7O3 |
| CAS# | 371942-69-7 |
| Inchi | InChI=1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17)22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8,13-14H,9-12H2,(H2,26,28)(H,29,33) |
| Inchi Key | YBPIBGNBHHGLEB-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ym201636.html |
| Additional Information | https://file.selleck.cn/downloads/struct/YM201636-chemical-structure-s1219.gif |