YM201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue). YM-201636 suppresses the growth of liver cancer via the induction of autophagy.
| Trivial name | N/A |
| Catalog Number | S1219 |
| Molecular Formula | C20H25F3N6O3 |
| CAS# | 371942-69-7 |
| Inchi | InChI=1S/C20H25F3N6O3/c21-20(22,23)32-17-4-2-1-3-15(17)11-26-19-27-12-16(29(30)31)18(28-19)25-10-14-7-5-13(9-24)6-8-14/h1-4,12-14H,5-11,24H2,(H2,25,26,27,28) |
| Inchi Key | HKOWATVSFKRXRW-UHFFFAOYSA-N |
| SMILES | C1CC(CCC1CN)CNC2=NC(=NC=C2[N+](=O)[O-])NCC3=CC=CC=C3OC(F)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ym201636.html |
| Additional Information | https://file.selleck.cn/downloads/struct/YM201636-chemical-structure-s1219.gif |