YM201636
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α and insensitive to Fabl (yeast orthologue). YM-201636 suppresses the growth of liver cancer via the induction of autophagy.
Trivial name | N/A |
Catalog Number | S1219 |
Molecular Formula | C13H12FN5 |
CAS# | 371942-69-7 |
Inchi | InChI=1S/C13H12FN5/c1-15-12-11-13(17-7-16-12)19(8-18-11)6-9-4-2-3-5-10(9)14/h2-5,7-8H,6H2,1H3,(H,15,16,17) |
Inchi Key | MZABAGHILOTTOD-UHFFFAOYSA-N |
SMILES | CNC1=C2C(=NC=N1)N(C=N2)CC3=CC=CC=C3F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/ym201636.html |
Additional Information | https://file.selleck.cn/downloads/struct/YM201636-chemical-structure-s1219.gif |