Clofarabine
Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis.
| Trivial name | Clolar |
| Catalog Number | S1218 |
| Molecular Formula | C11H7IN2O4 |
| CAS# | 123318-82-1 |
| Inchi | InChI=1S/C11H7IN2O4/c12-7-1-3-8(4-2-7)13-11(15)9-5-6-10(18-9)14(16)17/h1-6H,(H,13,15) |
| Inchi Key | JBIKQXOZLBLMKI-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])I |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Clofarabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Clofarabine-chemical-structure-S1218.gif |