PFI-1 (PF-6405761)
PFI-1 (PF-6405761) is a highly selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM and for BRD2 with IC50 of 98 nM in a cell-free assay.
Trivial name | N/A |
Catalog Number | S1216 |
Molecular Formula | C16H17N3O4S |
CAS# | 1403764-72-6 |
Inchi | InChI=1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20) |
Inchi Key | TXZPMHLMPKIUGK-UHFFFAOYSA-N |
SMILES | CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/pfl-1.html |
Additional Information | https://file.selleck.cn/downloads/struct/PF-06405761-chemical-structure-s1216.gif |