Doxorubicin (DOX) HCl

Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.

Price Not Available 10mg Doxorubicin (DOX) HCl Supplier Page
Trivial name Adriamycin, NSC 123127, Hydroxydaunorubicin HCl
Catalog Number S1208
Molecular Formula C27H29NO11.HCl
CAS# 25316-40-9
Inchi InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3; 1H/t10-,13-,15-,17-,22+,27-;/m0./s1
Inchi Key MWWSFMDVAYGXBV-RUELKSSGSA-N
SMILES CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O.Cl
Size 10mg
Supplier Page http://www.selleckchem.com/products/Adriamycin.html
Additional Information https://file.selleck.cn/downloads/struct/Adriamycin-Doxorubicin-chemical-structure-S1208.gif