Tivozanib
Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.
| Trivial name | AV-951, KRN-951 |
| Catalog Number | S1207 |
| Molecular Formula | C13H26N2O4 |
| CAS# | 475108-18-0 |
| Inchi | InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19) |
| Inchi Key | PAHZPHDAJQIETD-UHFFFAOYSA-N |
| SMILES | C(CCCC(=O)NCCO)CCCC(=O)NCCO |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/AV-951.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AV-951-Tivozanib-chemical-structure-S1207.gif |