Decitabine
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
| Trivial name | Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716 |
| Catalog Number | S1200 |
| Molecular Formula | C20H14Cl2FN5O2S |
| CAS# | 2353-33-5 |
| Inchi | InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27) |
| Inchi Key | GUYKCXXNIKKSBC-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Decitabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Decitabine-chemical-structure-S1200.gif |