Thalidomide
Thalidomide was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1.
| Trivial name | K17 |
| Catalog Number | S1193 |
| Molecular Formula | C17H16BrN3O2 |
| CAS# | 50-35-1 |
| Inchi | InChI=1S/C17H16BrN3O2/c1-21(12-6-4-5-11(18)7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3 |
| Inchi Key | IPWGDOZPSOZFOD-UHFFFAOYSA-N |
| SMILES | CN(C1=CC(=CC=C1)Br)C2=NC=NC3=CC(=C(C=C32)OC)OC |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Thalidomide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Thalidomide-chemical-structure-S1193.gif |