XAV-939

XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

Price Not Available 50mg XAV-939 Supplier Page
Trivial name NVP-XAV939
Catalog Number S1180
Molecular Formula C14H11F3N2OS
CAS# 284028-89-3
Inchi InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
Inchi Key KLGQSVMIPOVQAX-UHFFFAOYSA-N
SMILES C1CSCC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F
Size 50mg
Supplier Page http://www.selleckchem.com/products/XAV-939.html
Additional Information https://file.selleck.cn/downloads/struct/s1180-xav-939-chemical-structure.png