PD98059
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
| Trivial name | N/A |
| Catalog Number | S1177 |
| Molecular Formula | C25H25N3O2S |
| CAS# | 167869-21-8 |
| Inchi | InChI=1S/C25H25N3O2S/c29-22(18-4-2-1-3-5-18)28-24-27-20-7-6-19(11-21(20)31-24)26-23(30)25-12-15-8-16(13-25)10-17(9-15)14-25/h1-7,11,15-17H,8-10,12-14H2,(H,26,30)(H,27,28,29) |
| Inchi Key | MVSSJPGNLQPWSW-UHFFFAOYSA-N |
| SMILES | C1C2CC3CC1CC(C2)(C3)C(=O)NC4=CC5=C(C=C4)N=C(S5)NC(=O)C6=CC=CC=C6 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/PD-98059.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PD98059-chemical-structure-S1177.gif |