Serdemetan (JNJ-26854165)

Serdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.

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Trivial name	N/A
Catalog Number	S1172
Molecular Formula	C21H20N4
CAS#	881202-45-5
Inchi	InChI=1S/C21H20N4/c1-2-4-21-20(3-1)16(15-24-21)9-14-23-17-5-7-18(8-6-17)25-19-10-12-22-13-11-19/h1-8,10-13,15,23-24H,9,14H2,(H,22,25)
Inchi Key	CEGSUKYESLWKJP-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=CN2)CCNC3=CC=C(C=C3)NC4=CC=NC=C4
Size	25mg
Supplier Page	http://www.selleckchem.com/products/JNJ-26854165.html
Additional Information	https://file.selleck.cn/downloads/struct/JNJ-26854165-chemical-structure-S1172.gif