ABT-751 (E7010)
ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.
| Trivial name | N/A |
| Catalog Number | S1165 |
| Molecular Formula | C26H41Br2NO4 |
| CAS# | 141430-65-1 |
| Inchi | InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1 |
| Inchi Key | IKGXLCMLVINENI-UHFFFAOYSA-M |
| SMILES | CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C.[Br-] |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/ABT-751.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ABT-751-chemical-structure-S1165.gif |