Roscovitine
Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.
| Trivial name | CYC202, Seliciclib, R-roscovitine |
| Catalog Number | S1153 |
| Molecular Formula | C13H9Cl3N2O |
| CAS# | 186692-46-6 |
| Inchi | InChI=1S/C13H9Cl3N2O/c14-8-1-3-9(4-2-8)17-13(19)18-10-5-6-11(15)12(16)7-10/h1-7H,(H2,17,18,19) |
| Inchi Key | ICUTUKXCWQYESQ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Roscovitine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roscovitine-Seliciclib-chemical-structure-S1153.gif |