Roscovitine
Roscovitine is a potent and selective CDK inhibitor for Cdc2, CDK2 and CDK5 with IC50 of 0.65 μM, 0.7 μM and 0.16 μM in cell-free assays. It shows little effect on CDK4/6. Phase 2.
| Trivial name | CYC202, Seliciclib, R-roscovitine |
| Catalog Number | S1153 |
| Molecular Formula | C33H44N4O10 |
| CAS# | 186692-46-6 |
| Inchi | InChI=1S/C33H44N4O10/c1-7-11-25(38)44-18-24(46-27(40)13-9-3)30(47-28(41)14-10-4)23(45-26(39)12-8-2)17-37-22-16-20(6)19(5)15-21(22)34-29-31(37)35-33(43)36-32(29)42/h15-16,23-24,30H,7-14,17-18H2,1-6H3,( H,36,42,43)/t23-,24+,30-/m0/s1 |
| Inchi Key | MJNIWUJSIGSWKK-BBANNHEPSA-N |
| SMILES | CCCC(=O)OCC(C(C(CN1C2=C(C=C(C(=C2)C)C)N=C3C1=NC(=O)NC3=O)OC(=O)CCC)OC(=O)CCC)OC(=O)CCC |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Roscovitine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Roscovitine-Seliciclib-chemical-structure-S1153.gif |