Cyclopamine
Cyclopamine (11-deoxojervine) is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells.
| Trivial name | 11-deoxojervine |
| Catalog Number | S1146 |
| Molecular Formula | C27H41NO2 |
| CAS# | 4449-51-8 |
| Inchi | InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27- /m0/s1 |
| Inchi Key | QASFUMOKHFSJGL-LAFRSMQTSA-N |
| SMILES | CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Cyclopamine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Cyclopamine-chemical-structure-S1146.gif |