SNS-032 (BMS-387032)

SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.

Price Not Available 10mM/1mL SNS-032 (BMS-387032) Supplier Page
Trivial name N/A
Catalog Number S1145
Molecular Formula C17H24N4O2S2
CAS# 345627-80-7
Inchi InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)
Inchi Key OUSFTKFNBAZUKL-UHFFFAOYSA-N
SMILES CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC3
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/SNS-032.html
Additional Information https://file.selleck.cn/downloads/struct/SNS-032-BMS-387032-chemical-structure-S1145.gif