SNS-032 (BMS-387032)

SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.

Price Not Available 10mM/1mL SNS-032 (BMS-387032) Supplier Page

Trivial name	N/A
Catalog Number	S1145
Molecular Formula	C34H36FN5O2
CAS#	345627-80-7
Inchi	InChI=1S/C34H36FN5O2/c1-3-38(4-2)34(42)32(25-11-6-5-7-12-25)40-21-19-39(20-22-40)31-17-16-27(23-30(31)35)37-33(41)29-15-9-8-14-28(29)26-13-10-18-36-24-26/h5-18,23-24,32H,3-4,19-22H2,1-2H3,(H,37,41)
Inchi Key	OVUNRYUVDVWTTE-UHFFFAOYSA-N
SMILES	CCN(CC)C(=O)C(C1=CC=CC=C1)N2CCN(CC2)C3=C(C=C(C=C3)NC(=O)C4=CC=CC=C4C5=CN=CC=C5)F
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/SNS-032.html
Additional Information	https://file.selleck.cn/downloads/struct/SNS-032-BMS-387032-chemical-structure-S1145.gif