SNS-032 (BMS-387032)

SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis.

Price Not Available 50mg SNS-032 (BMS-387032) Supplier Page
Trivial name N/A
Catalog Number S1145
Molecular Formula C32H38ClN3O2
CAS# 345627-80-7
Inchi InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3
Inchi Key KJNNWYBAOPXVJY-UHFFFAOYSA-N
SMILES CCCCC1=NC(=CN1C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)C4=CC=C(C=C4)OCCCN(CC)CC
Size 50mg
Supplier Page http://www.selleckchem.com/products/SNS-032.html
Additional Information https://file.selleck.cn/downloads/struct/SNS-032-BMS-387032-chemical-structure-S1145.gif