Tanespimycin (17-AAG)

Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.

Price Not Available 25mg Tanespimycin (17-AAG) Supplier Page

Trivial name	CP127374, NSC-330507, KOS 953
Catalog Number	S1141
Molecular Formula	C18H27NO3
CAS#	75747-14-7
Inchi	InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6-
Inchi Key	YKPUWZUDDOIDPM-VURMDHGXSA-N
SMILES	CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Size	25mg
Supplier Page	http://www.selleckchem.com/products/17-AAG(Geldanamycin).html
Additional Information	https://file.selleck.cn/downloads/struct/17-AAG-Geldanamycin-chemical-structure-S1141.gif