Pemetrexed disodium
Pemetrexed disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
Trivial name | LY-231514 disodium |
Catalog Number | S1135 |
Molecular Formula | C7H7ClNNaO2S |
CAS# | 150399-23-8 |
Inchi | InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1 |
Inchi Key | VDQQXEISLMTGAB-UHFFFAOYSA-N |
SMILES | CC1=CC=C(C=C1)S(=O)(=O)[N-]Cl.[Na+] |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/Pemetrexed-disodium.html |
Additional Information | https://file.selleck.cn/downloads/struct/Pemetrexed-Alimta-chemical-structure-S1135.gif |