Mocetinostat (MGCD0103)
Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2.
Trivial name | MG0103 |
Catalog Number | S1122 |
Molecular Formula | C23H20N6O |
CAS# | 726169-73-9 |
Inchi | InChI=1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29) |
Inchi Key | HRNLUBSXIHFDHP-UHFFFAOYSA-N |
SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/MGCD0103(Mocetinostat).html |
Additional Information | https://file.selleck.cn/downloads/struct/MGCD0103-Mocetinostat-chemical-structure-S1122.gif |