Triciribine (API-2)
Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Trivial name | NSC 154020, VD-0002, vqd-002, TCN |
Catalog Number | S1117 |
Molecular Formula | C11H13NO3 |
CAS# | 35943-35-2 |
Inchi | InChI=1S/C11H13NO3/c1-8(13)12-10(11(14)15)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1 |
Inchi Key | CBQJSKKFNMDLON-JTQLQIEISA-N |
SMILES | CC(=O)NC(CC1=CC=CC=C1)C(=O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Triciribine.html |
Additional Information | https://file.selleck.cn/downloads/struct/Triciribine-chemical-structure-S1117.gif |