Palbociclib (PD-0332991) HCl
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
Trivial name | N/A |
Catalog Number | S1116 |
Molecular Formula | C24H29N7O2.HCl |
CAS# | 827022-32-2 |
Inchi | InChI=1S/C24H29N7O2.ClH/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32;/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29);1H |
Inchi Key | STEQOHNDWONVIF-UHFFFAOYSA-N |
SMILES | CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/PD-0332991.html |
Additional Information | https://file.selleck.cn/downloads/struct/PD-0332991-chemical-structure-s1116.gif |