Palbociclib (PD-0332991) HCl
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
Trivial name | N/A |
Catalog Number | S1116 |
Molecular Formula | C8H16N4O3 |
CAS# | 827022-32-2 |
Inchi | InChI=1S/C8H16N4O3/c1-5(13)12-6(7(14)15)3-2-4-11-8(9)10/h6H,2-4H2,1H3,(H,12,13)(H,14,15)(H4,9,10,11)/t6-/m0/s1 |
Inchi Key | SNEIUMQYRCDYCH-LURJTMIESA-N |
SMILES | CC(=O)NC(CCCN=C(N)N)C(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/PD-0332991.html |
Additional Information | https://file.selleck.cn/downloads/struct/PD-0332991-chemical-structure-s1116.gif |