BI 2536
BI-2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM in a cell-free assay. BI-2536 inhibits Bromodomain 4 (BRD4) with Kd of 37 nM and potently suppresses c-Myc expression. BI-2536 induces apoptosis and attenuates autophagy. Phase 2.
| Trivial name | N/A |
| Catalog Number | S1109 |
| Molecular Formula | C19H38O2 |
| CAS# | 755038-02-9 |
| Inchi | InChI=1S/C19H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21/h2-18H2,1H3,(H,20,21) |
| Inchi Key | ISYWECDDZWTKFF-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCC(=O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/BI-2536.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BI-2536-chemical-structure-S1109.gif |