Linsitinib (OSI-906)
Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
| Trivial name | N/A |
| Catalog Number | S1091 |
| Molecular Formula | C7H12O4 |
| CAS# | 867160-71-2 |
| Inchi | InChI=1S/C7H12O4/c1-7(2,3-5(8)9)4-6(10)11/h3-4H2,1-2H3,(H,8,9)(H,10,11) |
| Inchi Key | DUHQIGLHYXLKAE-UHFFFAOYSA-N |
| SMILES | CC(C)(CC(=O)O)CC(=O)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/OSI-906.html |
| Additional Information | https://file.selleck.cn/downloads/struct/OSI-906-chemical-structure-s1091.gif |