Tandutinib (MLN518)

Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.

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Trivial name	CT 53518, NSC726292, MLN518
Catalog Number	S1043
Molecular Formula	C31H42N6O4
CAS#	387867-13-2
Inchi	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
Inchi Key	UXXQOJXBIDBUAC-UHFFFAOYSA-N
SMILES	CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
Size	100mg
Supplier Page	http://www.selleckchem.com/products/Tandutinib-(MLN518).html
Additional Information	https://file.selleck.cn/downloads/struct/Tandutinib-MLN518-chemical-structure-S1043.gif