Tandutinib (MLN518)
Tandutinib (MLN518, CT53518, NSC726292) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2.
| Trivial name | CT 53518, NSC726292, MLN518 |
| Catalog Number | S1043 |
| Molecular Formula | C11H12O3 |
| CAS# | 387867-13-2 |
| Inchi | InChI=1S/C11H12O3/c1-8(12)2-3-9-4-5-10-11(6-9)14-7-13-10/h4-6H,2-3,7H2,1H3 |
| Inchi Key | TZJLGGWGVLADDN-UHFFFAOYSA-N |
| SMILES | CC(=O)CCC1=CC2=C(C=C1)OCO2 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Tandutinib-(MLN518).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Tandutinib-MLN518-chemical-structure-S1043.gif |
