Sunitinib malate

Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1α. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.

Price Not Available 500mg Sunitinib malate Supplier Page

Trivial name	SU11248 malate
Catalog Number	S1042
Molecular Formula	C22H27FN4O2.C4H6O5
CAS#	341031-54-7
Inchi	InChI=1S/C22H27FN4O2.C4H6O5/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28;5-2(4(8)9)1-3(6)7/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28);2,5H,1H2,(H,6,7 )(H,8,9)/b17-12-;/t;2-/m.0/s1
Inchi Key	LBWFXVZLPYTWQI-IPOVEDGCSA-N
SMILES	CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O
Size	500mg
Supplier Page	http://www.selleckchem.com/products/Sunitinib-Malate-(Sutent).html
Additional Information	https://file.selleck.cn/downloads/struct/Sunitinib-Sutent-chemical-structure-S1042.gif