Rapamycin
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
| Trivial name | Sirolimus, AY-22989, NSC-2260804 |
| Catalog Number | S1039 |
| Molecular Formula | C11H12O4 |
| CAS# | 53123-88-9 |
| Inchi | InChI=1S/C11H12O4/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)(H,14,15) |
| Inchi Key | GTOFKXZQQDSVFH-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CC(CC(=O)O)C(=O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Rapamycin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rapamycin-Sirolimus-chemical-structure-S1039.gif |