Rapamycin
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM in HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
| Trivial name | Sirolimus, AY-22989, NSC-2260804 |
| Catalog Number | S1039 |
| Molecular Formula | C13H25NO |
| CAS# | 53123-88-9 |
| Inchi | InChI=1S/C13H25NO/c1-5-14-13(15)12-8-10(4)6-7-11(12)9(2)3/h9-12H,5-8H2,1-4H3,(H,14,15) |
| Inchi Key | VUNOFAIHSALQQH-UHFFFAOYSA-N |
| SMILES | CCNC(=O)C1CC(CCC1C(C)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Rapamycin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rapamycin-Sirolimus-chemical-structure-S1039.gif |