Nilotinib
Nilotinib is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
| Trivial name | AMN-107 |
| Catalog Number | S1033 |
| Molecular Formula | C29H50O2 |
| CAS# | 641571-10-0 |
| Inchi | InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3 |
| Inchi Key | GVJHHUAWPYXKBD-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C)C(=C1O)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Nilotinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Nilotinib-AMN-107-chemical-structure-S1033.gif |