Motesanib Diphosphate (AMG-706)

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit (c-Kit), ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.

Price Not Available 10mg Motesanib Diphosphate (AMG-706) Supplier Page

Trivial name	N/A
Catalog Number	S1032
Molecular Formula	C10H12N4Na3O14P3
CAS#	857876-30-3
Inchi	InChI=1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p -3/t4-,6-,7-,10-;;;/m1.../s1
Inchi Key	QRGLCGLOQVQVCS-MSQVLRTGSA-K
SMILES	C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
Size	10mg
Supplier Page	http://www.selleckchem.com/products/Motesanib-Diphosphate.html
Additional Information	https://file.selleck.cn/downloads/struct/Motesanib-AMG-706-chemical-structure-S1032.gif