Imatinib Mesylate
Imatinib Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy.
Trivial name | CGP-57148B,STI571 |
Catalog Number | S1026 |
Molecular Formula | C29H31N7O.CH4SO3 |
CAS# | 220127-57-1 |
Inchi | InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,3 3,34);1H3,(H,2,3,4) |
Inchi Key | YLMAHDNUQAMNNX-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
Size | 250mg |
Supplier Page | http://www.selleckchem.com/products/Imatinib-Mesylate.html |
Additional Information | https://file.selleck.cn/downloads/struct/Imatinib-Mesylate-chemical-structure-S1026.gif |