Dasatinib
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
| Trivial name | BMS-354825 |
| Catalog Number | S1021 |
| Molecular Formula | C32H22N6Na2O6S2 |
| CAS# | 302962-49-8 |
| Inchi | InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40, 41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;; |
| Inchi Key | IQFVPQOLBLOTPF-HKXUKFGYSA-L |
| SMILES | C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+] |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Dasatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Dasatinib-BMS-354825-chemical-structure-S1021.gif |