Dovitinib (TKI-258)

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.

Price Not Available 10mg Dovitinib (TKI-258) Supplier Page

Trivial name	CHIR-258
Catalog Number	S1018
Molecular Formula	C10H16
CAS#	405169-16-6
Inchi	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m1/s1
Inchi Key	XMGQYMWWDOXHJM-SNVBAGLBSA-N
SMILES	CC1=CCC(CC1)C(=C)C
Size	10mg
Supplier Page	http://www.selleckchem.com/products/CHIR-258.html
Additional Information	https://file.selleck.cn/downloads/struct/Dovitinib-chemical-structure-s1018.gif