Roxadustat (FG-4592)
Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis. Phase 3.
Trivial name | ASP1517 |
Catalog Number | S1007 |
Molecular Formula | C19H16N2O5 |
CAS# | 808118-40-3 |
Inchi | InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23) |
Inchi Key | YOZBGTLTNGAVFU-UHFFFAOYSA-N |
SMILES | CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/fg-4592.html |
Additional Information | https://file.selleck.cn/downloads/struct/FG-4592-chemical-structure-s1007.gif |