Saracatinib (AZD0530)
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3.
| Trivial name | N/A |
| Catalog Number | S1006 |
| Molecular Formula | C27H32ClN5O5 |
| CAS# | 379231-04-6 |
| Inchi | InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31) |
| Inchi Key | OUKYUETWWIPKQR-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/AZD0530.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Saracatinib-AZD0530-chemical-structure-S1006.gif |