Axitinib
Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
| Trivial name | AG 013736 |
| Catalog Number | S1005 |
| Molecular Formula | C22H18N4OS |
| CAS# | 319460-85-0 |
| Inchi | InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+ |
| Inchi Key | RITAVMQDGBJQJZ-FMIVXFBMSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Axitinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Axitinib-chemical-structure-S1005.gif |