Veliparib (ABT-888)
Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3.
| Trivial name | NSC 737664 |
| Catalog Number | S1004 |
| Molecular Formula | C3H4N2 |
| CAS# | 912444-00-9 |
| Inchi | InChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5) |
| Inchi Key | RAXXELZNTBOGNW-UHFFFAOYSA-N |
| SMILES | C1=CN=CN1 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ABT-888.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ABT-888-Veliparib-chemical-structure-S1004.gif |