Cediranib (AZD2171)

Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.

Price Not Available 10mM/1mL Cediranib (AZD2171) Supplier Page

Trivial name	NSC-732208
Catalog Number	S1017
Molecular Formula	C8H16N2O3
CAS#	288383-20-0
Inchi	InChI=1S/C8H16N2O3/c1-5(2)3-6(8(12)13)10-7(11)4-9/h5-6H,3-4,9H2,1-2H3,(H,10,11)(H,12,13)/t6-/m0/s1
Inchi Key	DKEXFJVMVGETOO-LURJTMIESA-N
SMILES	CC(C)CC(C(=O)O)NC(=O)CN
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/Cediranib.html
Additional Information	https://file.selleck.cn/downloads/struct/Cediranib-AZD2171-chemical-structure-S1017.gif